MB-07344
MB-07344 is a potent thyroid hormone receptor (TR) -β agonist with a Ki of 2.17 nM. MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys[1].
Product Specifications
CAS Number
852947-39-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/mb-07344.html
Purity
99.86
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC1=C(CC2=CC=C(O)C(C(C)C)=C2)C(C)=CC(OCP(O)(O)=O)=C1
Molecular Formula
C19H25O5P
Molecular Weight
364.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Ito BR, et al. Thyroid hormone beta receptor activation has additive cholesterol lowering activity in combination with atorvastatin in rabbits, dogs and monkeys. Br J Pharmacol. 2009 Feb;156 (3) :454-65.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81231/imageurl/et7106-88.webp)
ET7106-88 100 µL
GABA B Receptor 2 Recombinant Rabbit Monoclonal Antibody [JU31-32]
Sign In for Pricing
View Details 
RD-QSOX1-Hu-01 96 Tests
Human Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1) ELISA Kit
Sign In for Pricing
View Details RD-QSOX1-Hu-02 48 Tests
Human Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1) ELISA Kit
Sign In for Pricing
View Details