Corticosterone (Standard)
Corticosterone (Standard) is the analytical standard of Corticosterone. This product is intended for research and analytical applications. Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala) . Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect[1][2][3][4].
Product Specifications
CAS Number
[50-22-6]
Product Name Alternative
17-Deoxycortisol (Standard) ; 11β,21-Dihydroxyprogesterone (Standard) ; Kendall's compound B (Standard)
UNSPSC
12352211
Hazard Statement
H317
Target
Endogenous Metabolite; Glucocorticoid Receptor; iGluR; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/corticosterone-standard.html
Purity
99.70
Smiles
C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Molecular Formula
C21H30O4
Molecular Weight
346.46
Precautions
H317
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Phase 3
Isoform
AMPA Receptor; Human Endogenous Metabolite
Available Sizes
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