Senecionine acetate

Senecionine acetate (O-Acetylsenecionine) is a pyrrolizidine alkaloid. Senecionine acetate inhibits the sequestration of Ca2+ in extramitochondrial and mitochondrial compartments possibly by inactivating free sulfhydryl groups[1].

Product Specifications

CAS Number

[126642-77-1]

Product Name Alternative

O-Acetylsenecionine

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/senecionine-acetate.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@]1([H])CCN2[C@]1([H])C(COC([C@](C)(OC(C)=O)[C@H](C)C/3)=O)=CC2)C3=C/C

Molecular Formula

C20H27NO6

Molecular Weight

377.43

References & Citations

[1]D S Griffin, et al. Effects of the pyrrolizidine alkaloid senecionine and the alkenals trans-4-OH-hexenal and trans-2-hexenal on intracellular calcium compartmentation in isolated hepatocytes. Biochem Pharmacol. 1989 Feb 1;38 (3) :391-7.