Senecionine acetate
Product Specifications
UNSPSC Description
Senecionine acetate (O-Acetylsenecionine) is a pyrrolizidine alkaloid. Senecionine acetate inhibits the sequestration of Ca2+ in extramitochondrial and mitochondrial compartments possibly by inactivating free sulfhydryl groups[1].
Target Antigen
Mitochondrial Metabolism
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/senecionine-acetate.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@]1([H])CCN2[C@]1([H])C(COC([C@](C)(OC(C)=O)[C@H](C)C/3)=O)=CC2)C3=C/C
Molecular Weight
377.43
References & Citations
[1]D S Griffin, et al. Effects of the pyrrolizidine alkaloid senecionine and the alkenals trans-4-OH-hexenal and trans-2-hexenal on intracellular calcium compartmentation in isolated hepatocytes. Biochem Pharmacol. 1989 Feb 1;38(3):391-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7594/Senecionine-acetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7594/
Clinical Information
No Development Reported
CAS Number
126642-77-1
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