LUF6283
LUF6283 is a potent and orally active HCA (2) partial agonist, with a Ki of 0.55 µM. LUF6283 can achieve the beneficial lipid lowering effect of niacin without producing the unwanted cutaneous flushing side effect[1].
Product Specifications
CAS Number
92933-48-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Hydroxycarboxylic Acid Receptor (HCAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/luf6283.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=NNC(CCCC)=C1)O
Molecular Formula
C8H12N2O2
Molecular Weight
168.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Li Z, et al. Effects of pyrazole partial agonists on HCA (2) -mediated flushing and VLDL-triglyceride levels in mice. Br J Pharmacol. 2012 Oct;167 (4) :818-25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
104431R0-AAT 25 Tests
PE/iFluor® 750 Anti-human CD44 Antibody *HERMES-1*
Sign In for Pricing
View Details 10-4097-100 100 µg
Monoclonal Antibody to Human IL-17 RA (Clone: ABM39B1)
Sign In for Pricing
View Details