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Mavacoxib

Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID) . Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs[1].

Product Specifications

CAS Number

170569-88-7

UNSPSC

12352005

Hazard Statement

H360, H373, H412

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mavacoxib.html

Purity

99.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC=C(F)C=C3)C=C1)(N)=O

Molecular Formula

C16H11F4N3O2S

Molecular Weight

385.34

Precautions

H360, H373, H412

References & Citations

[1]Hurst EA, et al. The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxil) exerts anti-tumour effects in vitro independent of cyclooxygenase-2 expression levels. Vet Comp Oncol. 2019 Jun;17 (2) :194-207.|[2]Cox SR, et al. Population pharmacokinetics of mavacoxib in osteoarthritic dogs. J Vet Pharmacol Ther. 2011 Feb;34 (1) :1-11.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

Available Sizes

Frequently Asked Questions

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