Mavacoxib
Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID) . Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs[1].
Product Specifications
CAS Number
[170569-88-7]
UNSPSC
12352005
Hazard Statement
H360, H373, H412
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mavacoxib.html
Purity
99.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC=C(F)C=C3)C=C1)(N)=O
Molecular Formula
C16H11F4N3O2S
Molecular Weight
385.34
Precautions
H360, H373, H412
References & Citations
[1]Hurst EA, et al. The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxil) exerts anti-tumour effects in vitro independent of cyclooxygenase-2 expression levels. Vet Comp Oncol. 2019 Jun;17 (2) :194-207.|[2]Cox SR, et al. Population pharmacokinetics of mavacoxib in osteoarthritic dogs. J Vet Pharmacol Ther. 2011 Feb;34 (1) :1-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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