TPU-0037A

TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs=1.56-12.5 μg/mL), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs=>50 μg/mL) .

Product Specifications

CAS Number

[485815-59-6]

Product Name Alternative

Antibiotic TPU-0037-A

UNSPSC

12352005

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tpu-0037a.html

Smiles

O=C(C1=C(CNC1=O)O)C2(C3C(C(C(O)CC3)O)C=C(C)C-;@2CCC(C)C(O)/C(C)=C/CC(O)/C=C/C(C)C(O)/C=C/CC(O)/C=C/CC(O)CC4N(CCC4)C(N)=N)C

Molecular Formula

C46H72N4O10

Molecular Weight

841.08

References & Citations

[1]Furumai, et al. TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. J. Antibiot. (Tokyo) 55 (10), 873-880 (2002) .