HSD17B1 Rabbit Polyclonal Antibody

Product Specifications

Product Name Alternative

Estradiol 17-beta-dehydrogenase 1; 1.1.1.62; 17-beta-hydroxysteroid dehydrogenase type 1; 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Placental 17-beta-hydroxysteroid dehydrogenase; Short chain dehydrogenase/reductase family 28C member 1; HSD17B1; E17KSR, EDH17B1, EDH17B2, EDHB17, SDR28C1

UniProt

P14061

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human HSD17B1, different from the related rat and mouse sequences by one amino acid.

Target

17-beta-hydroxysteroid dehydrogenase type 1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cancer Biology, Metabolism Research, Neuroscience, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Dilution

Western blot, 0.1-0.5μg/ml, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat Immunocytochemistry, 0.5-1μg/ml, Human

Form

Lyophilized

Molecular Weight

37-38 kDa

References & Citations

Yang, Yan et al. Directed mouse embryonic stem cells into leydig-like cells rescue testosterone-deficient male rats in vivo Stem Cells Dev, 24, 459-470 (2015), Kozlowska, Wiktoria et al. Electromagnetic field exposure alters in vitro estrogen biosynthesis and its release by the porcine endometrium in the peri-implantation period Reprod Biol, 22, 100642 (2022)

Pubmed id

25340537, 35487179

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IHC, WB

Host or Source

Rabbit

Preservative

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.