Djenkolic acid

Djenkolic acid is a sulfur-containing amino acid. Djenkolic acid can be isolated from the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic acid de-inhibits the SO42- uptake system in Pseudomonas fluorescens. Djenkolic acid causes supersaturation of the urinary system with djenkolic acid crystals, leading to urinary tract obstruction and acute kidney injury[1][2].

Product Specifications

CAS Number

[498-59-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Endocrinology

Assay Protocol

https://www.medchemexpress.com/djenkolic-acid.html

Purity

98.0

Solubility

1 M HCl : 20 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic; adjust pH to 1 with HCl)

Smiles

N[C@@H](CSCSC[C@@H](C(O)=O)N)C(O)=O

Molecular Formula

C7H14N2O4S2

Molecular Weight

254.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Nur C Bunawan, et al. Djenkolism: case report and literature review. Int Med Case Rep J. 2014 Apr 16;7:79-84.|[2]Ohtake H, et al. Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid. J Bacteriol. 1987 Aug;169 (8) :3853-6.