AMI-408
AMI-408 is a PRMT1 inhibitor. AMI-408 can reduce H4R3me2as level in MLL-GAS7 leukemia cells[1].
Product Specifications
CAS Number
78866-14-5
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ami-408.html
Smiles
O=S(C1=C(/N=N/C2=CC=C(OC)C=C2)C(O)=C3C=CC(NC4=NC(Cl)=NC(Cl)=N4)=CC3=C1)(O[Na])=O
Molecular Formula
C20H13Cl2N6NaO5S
Molecular Weight
543.32
References & Citations
[1]Cheung N, et al. Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia. Cancer Cell. 2016 Jan 11;29 (1) :32-48.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT1
Frequently Asked Questions
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