Pentabromopseudilin
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa) . PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer[1].
Product Specifications
CAS Number
[10245-81-5]
Product Name Alternative
AZD0865
UNSPSC
12352005
Target
Antibiotic; TGF-β Receptor
Type
Reference compound
Related Pathways
Anti-infection; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pentabromopseudilin.html
Purity
99.63
Solubility
DMSO : ≥ 125 mg/mL
Smiles
OC1=C(C2=C(Br)C(Br)=C(Br)N2)C=C(Br)C=C1Br
Molecular Formula
C10H4Br5NO
Molecular Weight
553.66
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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