Agaric acid
Agaric acid (Agaricinic Acid) is an orally active inhibitor of adenine nucleotide translocase found in specific fungi. Agaric acid can inhibit the biofilm formation of various bacteria such as Salmonella. Agaric acid can also induce mitochondrial permeability transition, prompting mitochondria to release Ca2+, disrupting the transmembrane potential, and causing mitochondrial swelling. In addition, Agaric acid can also inhibit citrate transport in liver mitochondria and participate in the inhibition of fatty acid synthesis, affecting multiple metabolic processes[1][2][3][4].
Product Specifications
CAS Number
666-99-9
Product Name Alternative
Agaricinic Acid
UNSPSC
12352211
Target
Bacterial; Calcium Channel; Mitochondrial Metabolism
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/agaric-acid.html
Purity
99.45
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCCCC(C(O)=O)C(C(O)=O)(O)CC(O)=O
Molecular Formula
C22H40O7
Molecular Weight
416.55
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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