C8 D-threo Ceramide (d18:1/8:0)
C8 D-threo Ceramide (d18:1/8:0) is a sphingolipid analog that can effectively induce apoptosis in U937 cells and cause fragmentation of nucleosomal DNA[1].
Product Specifications
CAS Number
175892-43-0
UNSPSC
12352211
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
CCCCCCCC(N[C@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O
Molecular Formula
C26H51NO3
Molecular Weight
425.69
References & Citations
[1]N Karasavvas, et al. Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine. The ceramide amide group is not required for apoptosis. Eur J Biochem. 1996 Mar 1;236 (2) :729-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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