Phenibut (hydrochloride)

Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist[1]. Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects[2].

Product Specifications

CAS Number

[3060-41-1]

Product Name Alternative

β-Phenyl-GABA (hydrochloride) ; 4-Amino-3-phenylbutanoic acid (hydrochloride) ; 4-Amino-3-phenylbutyric acid hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/phenibut-hydrochloride.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CC(C1=CC=CC=C1)CN.[H]Cl

Molecular Formula

C10H14ClNO2

Molecular Weight

215.68

Precautions

H302, H315, H319, H335

References & Citations

[1]Ahuja T, et al. Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: EmergingNootropics of Abuse. Case Rep Psychiatry. 2018 Apr 30;2018:9864285.|[2]Lapin I. Phenibut (beta-phenyl-GABA) : a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7 (4) :471-81.