Biperiden-d5 (hydrochloride)
Biperiden-d5 (hydrochloride) is the deuterium labeled Biperiden hydrochloride. Biperiden (KL 373) hydrochloride is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.
Product Specifications
Product Name Alternative
KL 373-d5 (hydrochloride)
UNSPSC
12352005
Target
Isotope-Labeled Compounds; mAChR
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(CCN1CCCCC1)(C2CC3C=CC2C3)C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H].Cl
Molecular Formula
C21H25D5ClNO
Molecular Weight
352.95
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Pehl C, et al. Effects of two anticholinergic drugs, trospium chloride and biperiden, on motility and evoked potentials of the oesophagus. Aliment Pharmacol Ther. 1998 Oct;12 (10) |[3]Kornhuber J, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6 (8) |[4]Myhrer T, et al. Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats. Pharmacol Biochem Behav. 2008 Jun;89 (4) :633-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
MAChR1
Available Sizes
Frequently Asked Questions
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