Human β-defensin-1
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria[1].
Product Specifications
CAS Number
452274-53-2
Product Name Alternative
HβD-1
UNSPSC
12352209
Target
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/human-β-defensin-1.html
Purity
99.33
Smiles
O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(N)=O)C(N[C@@H](CSSC[C@@H]3NC4=O)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(NCC(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@H]4CCCCN)=O)=O)=O)=O)=O)=O)NC6=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(O)=O)=O)NC3=O)C(N8[C@@H](CCC8)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC9=CC=CC=C9)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(NCC(N[C@H]6[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molecular Formula
C167H256N48O50S6
Molecular Weight
3928.53
References & Citations
[1]Judith Raschig, et al. Ubiquitously Expressed Human Beta Defensin 1 (hBD1) Forms Bacteria-Entrapping Nets in a Redox Dependent Mode of Action. PLoS Pathog. 2017 Mar 21;13 (3) :e1006261.|[2]E V Valore, et al. Human beta-defensin-1: An Antimicrobial Peptide of Urogenital Tissues.J Clin Invest. 1998 Apr 15;101 (8) :1633-42.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Cr1341-inquire Inquire
Recombinant Treponema Pallidum TP_0110 Protein (aa 1-577)
Sign In for Pricing
View Details 