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GSK3-IN-1

GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1].

Product Specifications

CAS Number

478482-74-5

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

GSK-3

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gsk3-in-1.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 52°C)

Smiles

ClC1=C(CSC2=NN=C(C3=CC=NC=C3)O2)C=CC=C1

Molecular Formula

C14H10ClN3OS

Molecular Weight

303.77

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Lars Naerum, et al. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12 (11) :1525-8.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Dedicated for Diverse Library

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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