GSK3-IN-1
GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1].
Product Specifications
CAS Number
478482-74-5
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gsk3-in-1.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 52°C)
Smiles
ClC1=C(CSC2=NN=C(C3=CC=NC=C3)O2)C=CC=C1
Molecular Formula
C14H10ClN3OS
Molecular Weight
303.77
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Lars Naerum, et al. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12 (11) :1525-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Available Sizes
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