Venlafaxine (hydrochloride)

Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT) /norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

Product Specifications

CAS Number

[99300-78-4]

Product Name Alternative

Wy 45030 hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Venlafaxine-hydrochloride.html

Purity

99.76

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

OC1(C(C2=CC=C(OC)C=C2)CN(C)C)CCCCC1.Cl

Molecular Formula

C17H28ClNO2

Molecular Weight

313.86

Precautions

H302, H315, H319, H335

References & Citations

[2]Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121 (1-2) :70-5.|[1]Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25 (6) :871-80.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

J Agric Food Chem. 2021 Nov 17;69 (45) :13618-13627.|Water Res. 2025 Oct 1;288 (Pt B) :124709.|Int Immunopharmacol. 2025 Jan 6:147:113969.|J Med Chem. 2025 May 8;68 (9) :9176-9201.|Neurosci Bull. 2025 Jul;41 (7) :1229-1245.