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IIQLPEIVVV (TFA)

Product Specifications

UNSPSC Description

IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction. IIQLPEIVVV TFA can distinguish physiological from pathological fission and block physiological fission, thus leading to mitochondrial dysfunction. IIQLPEIVVV TFA can be used in the study of Huntington's disease[1].

Target Antigen

Dynamin

Type

Peptides

Related Pathways

Cytoskeleton

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/iiqlpeivvv-tfa.html

Purity

98.42

Smiles

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N.OC(C(F)(F)F)=O.[x]

Molecular Weight

1122.40 (free base)

References & Citations

[1]Kornfeld O S, et al. Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo[J]. Scientific reports, 2018, 8(1): 14034.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P6374/IIQLPEIVVV-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P6374/IIQLPEIVVV-TFA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Curated Selection

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