Octachlorodibenzo-p-dioxin
Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant but is not acutely toxic. In rats, Octachlorodibenzo-p-dioxin (50 μg/kg i.v. or 50-5000 μg/kg p.o.) has a systemic elimination half-life of 3-5 months and accumulates and concentrates in the liver and adipose tissue after low-dose, repeated exposure. Repeated administration of octachlorodibenzo-p-dioxin causes increases in 7-ethoxyresorufin-O-deethylase (7-EROD) activity and total cytochrome P-450 levels[1].
Product Specifications
CAS Number
[3268-87-9]
Product Name Alternative
OCDD
UNSPSC
12352005
Hazard Statement
H300-H410
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/octachlorodibenzo-p-dioxin.html
Smiles
ClC1=C(Cl)C2=C(OC3=C(O2)C(Cl)=C(Cl)C(Cl)=C3Cl)C(Cl)=C1Cl
Molecular Formula
C12Cl8O2
Molecular Weight
459.75
Precautions
P264-P270-P273-P330-P391-P405-P501
References & Citations
[1]Birnbaum LS, et al. Disposition of octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 1988 Mar 30;93 (1) :22-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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