Protein Kinase A Inhibitor Fragment 6-22 amide

<strong>Protein Kinase A Inhibitor Fragment 6-22 amide</strong>_x000D_ <strong>Catalog number:</strong> B2019315_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1868.06_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Protein Kinase A Inhibitor Fragment 6-22 amide_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Saidy B, Vasan R, Durant R, Greener MR, Immanuel A, Green AR, Rakha E, Ellis I, Ball G, Martin SG, Storr SJ. Unravelling transcriptomic complexity in breast cancer through modulation of DARPP-32 expression and signalling pathways Sci Rep. 2023 Nov 30;13(1):21163._x000D_ 2: Glass DB, Trewhella J, Mitchell RD, Walsh DA. Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase Protein Sci. 1995 Mar;4(3):405-15._x000D_ 3: Katz BM, Lundquist LJ, Walsh DA, Glass DB. Synthesis, characterization and inhibitory activities of (4-N3[3,5-3H]Phe10)PKI(6-22)amide and its precursors: photoaffinity labeling peptides for the active site of cyclic AMP-dependent protein kinase Int J Pept Protein Res. 1989 Jun;33(6):439-45._x000D_ 4: Dalton GD, Smith FL, Smith PA, Dewey WL. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI) Neuropharmacology. 2005 Apr;48(5):648-57._x000D_ 5: Grandjean-Laquerriere A, Le Naour R, Gangloff SC, Guenounou M. Differential regulation of TNF-alpha, IL-6 and IL-10 in UVB-irradiated human keratinocytes via cyclic AMP/protein kinase A pathway Cytokine. 2003 Aug 21-Sep 7;23(4-5):138-49._x000D_ 6: Dai K, Yan R, Li S, Fan Y, Zhuang F, Ruan C. Prolonged inhibition of protein kinase A results in metalloproteinase-dependent platelet GPIbalpha shedding Thromb Res. 2009 May;124(1):101-9._x000D_ 7: Koshimizu H, Cawley NX, Kim T, Yergey AL, Loh YP. Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells Mol Endocrinol. 2011 May;25(5):732-44._x000D_ 8: Howard DR, Habermacher G, Glass DB, Smith EF, Sale WS. Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase J Cell Biol. 1994 Dec;127(6 Pt 1):1683-92._x000D_ 9: Fusi F, Trezza A, Spiga O, Sgaragli G, Bova S. Ca(v)1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies Biochem Pharmacol. 2017 Sep 15;140:53-63._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8593818">10: Fortunati N, Fissore F, Fazzari A, Becchis M, Comba A, Catalano MG, Berta L, Frairia R. Sex steroid binding protein exerts a negative control on estradiol action in MCF-7 cells (human breast cancer) through cyclic adenosine 3',5'-monophosphate and protein kinase A Endocrinology. 1996 Feb;137(2):686-92. </a>_x000D_ _x000D_ <strong>Products Related to Protein Kinase A Inhibitor Fragment 6-22 amide can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>