Neramexane (mesylate)
Neramexane mesylate is an α9α10 cholinergic nicotinic receptors and N-methyl-D-aspartate receptors (NMDA) antagonist. Neramexane mesylate can improve moderate to severe tinnitus, and also shows neuroprotective effects[1][1].
Product Specifications
CAS Number
457068-92-7
UNSPSC
12352211
Target
IGluR; nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neramexane-mesylate.html
Smiles
NC1(CC(C)(CC(C)(C1)C)C)C.CS(=O)(O)=O
Molecular Formula
C12H27NO3S
Molecular Weight
265.41
References & Citations
[1]Suckfüll M, et al. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of neramexane in patients with moderate to severe subjective tinnitus. BMC Ear Nose Throat Disord. 2011;11:1. Published 2011 Jan 11. |[2]Sukhotina IA, et al. Caffeine withdrawal syndrome in social interaction test in mice: effects of the NMDA receptor channel blockers, memantine and neramexane. Behav Pharmacol. 2004;15 (3) :207-214.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
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