SMARCA2/4-ligand-3
SMARCA2/4-ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). SMARCA2/4-ligand-3 can be used for synthesis PROTAC SMARCA2/4-degrader-25.
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smarca2-4-ligand-3.html
Smiles
O=S(C1=CC=C([N+]([O-])=O)C=C1)(OC2=CC=CC=C2C3=NN=C(N)C(N4CCN(CC(O)=O)CC4)=C3)=O
Molecular Formula
C22H22N6O7S
Molecular Weight
514.51
References & Citations
[1]Ji M, et al. Glutathione-dependent degradation of SMARCA2/4 for targeted lung cancer therapy with improved selectivity. Eur J Med Chem. 2024 Nov 5;277:116751.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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