Dectrekumab
Dectrekumab (QAX576) is a human monoclonal antibody that targets IL-13. Dectrekumab significantly improves intraepithelial esophageal eosinophil counts and dysregulated esophageal disease-related transcripts with Eosinophilic esophagitis (EoE) in a sustained manner and can be used for inflammation and immunology related research[1].
Product Specifications
CAS Number
[1528523-94-5]
Product Name Alternative
QAX576
UNSPSC
12352203
Target
Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dectrekumab.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
[Dectrekumab]
Molecular Weight
(146.02 kDa)
References & Citations
[1]Rothenberg ME, et.al. Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2015 Feb;135 (2) :500-7.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Isoform
IL-13
Available Sizes
Curated Selection
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