N- (Aminooxy-PEG2) -N-bis (PEG3-propargyl)

N- (Aminooxy-PEG2) -N-bis (PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Aminooxy-PEG2) -N-bis (PEG3-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2112737-71-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-aminooxy-peg2-n-bis-peg3-propargyl.html

Purity

99.78

Solubility

10 mM in DMSO

Smiles

NOCCOCCOCCN(CCOCCOCCOCC#C)CCOCCOCCOCC#C

Molecular Formula

C24H44N2O9

Molecular Weight

504.61

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562