2-Thiothymidine
2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
28585-51-5
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-thiothymidine.html
Purity
99.75
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=S)O[C@@H]1CO
Molecular Formula
C10H14N2O4S
Molecular Weight
258.29
Precautions
H302, H315, H320, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
RASGRP1 sgRNA CRISPR Lentivector (Human) (Target 3)
Multiplex Assay Kit for Cysteine Rich Protein 1, Intestinal (CRIP1), etc. by FLIA (Flow Luminescence Immunoassay)
C19orf61/SMG9 Rabbit Polyclonal Antibody (Fluoro647)