Broussonin C

Broussonin C is a competitive inhibitor of Tyrosinase that can be isolated from Broussonetia kazinoki. Broussonin C inhibits monophenolase and diphenolase with IC50s of 0.43 and 0.57 μM, respectively[1].

Product Specifications

CAS Number

[76045-49-3]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/broussonin-c.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(CCCC2=CC=C(O)C(C/C=C(C)\C)=C2)C(O)=C1

Molecular Formula

C20H24O3

Molecular Weight

312.40

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Baek YS, et al. Rengasamy R, Yang MS, Park KH. Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki. Bioorg Med Chem. 2009 Jan 1;17 (1) :35-41.