JNJ-7925476 (hydrochloride)
JNJ-7925476 (hydrochloride) is a triple monoamine uptake inhibitor with the ability to regulate neurotransmitter levels and antidepressant activity. JNJ-7925476 (hydrochloride) can be rapidly absorbed into the plasma in rats, with a higher concentration in the brain than in plasma. It can induce an increase in the levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibits antidepressant activity in the mouse tail suspension test.
Product Specifications
CAS Number
109085-56-5
UNSPSC
12352005
Target
Adrenergic Receptor; Dopamine Transporter; Monoamine Transporter
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/jnj-7925476-hydrochloride.html
Smiles
C#CC1=CC=C(C=C1)[C@H]2C3=CC=CC=C3[C@]4([H])N(CCC4)C2.Cl
Molecular Formula
C20H20ClN
Molecular Weight
309.83
References & Citations
[1]In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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