Human TPO (Thrombopoietin)

<strong>Human TPO (Thrombopoietin)</strong>_x000D_ <strong>Catalog number:</strong> B2018648_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~19 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> TPO, Thrombopoietin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bussel JB, Soff G, Balduzzi A, Cooper N, Lawrence T, Semple JW. A Review of Romiplostim Mechanism of Action and Clinical Applicability Drug Des Devel Ther. 2021 May 26;15:2243-2268._x000D_ 2: Ishida A, Handa M. [Thrombopoietin (TPO)] Nihon Rinsho. 2005 Aug;63 Suppl 8:618-20._x000D_ 3: Zheng C, Yang R, Han Z, Zhou B, Liang L, Lu M. TPO-independent megakaryocytopoiesis Crit Rev Oncol Hematol. 2008 Mar;65(3):212-22._x000D_ 4: Basciano PA, Bussel JB. Thrombopoietin-receptor agonists Curr Opin Hematol. 2012 Sep;19(5):392-8._x000D_ 5: Bolam S. Thrombopoietin Transfus Sci. 1997 Mar;18(1):129-37._x000D_ 6: Geddis AE. Megakaryopoiesis Semin Hematol. 2010 Jul;47(3):212-9._x000D_ 7: Wei P. Thrombopoietin factors Cancer Treat Res. 2011;157:75-93._x000D_ 8: Soff G, Leader A, Al-Samkari H, Falanga A, Maraveyas A, Sanfilippo K, Wang TF, Zwicker J. Management of chemotherapy-induced thrombocytopenia: guidance from the ISTH Subcommittee on Hemostasis and Malignancy J Thromb Haemost. 2024 Jan;22(1):53-60._x000D_ 9: Ratajczak MZ, Ratajczak J, Marlicz W, Pletcher CH Jr, Machalinski B, Moore J, Hung H, Gewirtz AM. Recombinant human thrombopoietin (TPO) stimulates erythropoiesis by inhibiting erythroid progenitor cell apoptosis Br J Haematol. 1997 Jul;98(1):8-17._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21262827">10: Rongvaux A, Willinger T, Takizawa H, Rathinam C, Auerbach W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Eynon EE, Stevens S, Manz MG, Flavell RA. Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2378-83. </a>_x000D_ _x000D_ <strong>Products Related to Human TPO (Thrombopoietin) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>