Cathepsin Inhibitor Peptide

<strong>Cathepsin Inhibitor Peptide</strong>_x000D_ <strong>Catalog number:</strong> B2019199_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> Cathepsin inhibitor I; Z-FG-NHO-Bz; CATI -1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yoon MC, Solania A, Jiang Z, Christy MP, Podvin S, Mosier C, Lietz CB, Ito G, Gerwick WH, Wolan DW, Hook G, O'Donoghue AJ, Hook V. Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions ACS Chem Biol. 2021 Sep 17;16(9):1628-1643._x000D_ 2: Petruzzella A, Bruand M, Santamaria-Martínez A, Katanayeva N, Reymond L, Wehrle S, Georgeon S, Inel D, van Dalen FJ, Viertl D, Lau K, Pojer F, Schottelius M, Zoete V, Verdoes M, Arber C, Correia BE, Oricchio E. Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins Nat Chem Biol. 2024 Sep;20(9):1188-1198._x000D_ 3: Andrault PM, Samsonov SA, Weber G, Coquet L, Nazmi K, Bolscher JG, Lalmanach AC, Jouenne T, Brömme D, Pisabarro MT, Lalmanach G, Lecaille F. Antimicrobial Peptide LL-37 Is Both a Substrate of Cathepsins S and K and a Selective Inhibitor of Cathepsin L Biochemistry. 2015 May 5;54(17):2785-98._x000D_ 4: Lecaille F, Chazeirat T, Saidi A, Lalmanach G. Cathepsin V: Molecular characteristics and significance in health and disease Mol Aspects Med. 2022 Dec;88:101086._x000D_ 5: Saegusa K, Ishimaru N, Yanagi K, Arakaki R, Ogawa K, Saito I, Katunuma N, Hayashi Y. Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity J Clin Invest. 2002 Aug;110(3):361-9._x000D_ 6: Kaur R, Raghav N. Some thiocarbamoyl based novel anticathepsin agents Bioorg Chem. 2020 Nov;104:104174._x000D_ 7: Seo SU, Woo SM, Min KJ, Kwon TK. Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression Biochem Biophys Res Commun. 2018 Apr 15;498(4):849-854._x000D_ 8: Deal C. Future therapeutic targets in osteoporosis Curr Opin Rheumatol. 2009 Jul;21(4):380-5._x000D_ 9: Wieczerzak E, Rodziewicz-Motowidło S, Jankowska E, Giełdoń A, Ciarkowski J. An enormously active and selective azapeptide inhibitor of cathepsin B J Pept Sci. 2007 Aug;13(8):536-43._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20302511">10: Coppini LP, Barros NM, Oliveira M, Hirata IY, Alves MF, Paschoalin T, Assis DM, Juliano MA, Puzer L, Brömme D, Carmona AK. Plasminogen hydrolysis by cathepsin S and identification of derived peptides as selective substrate for cathepsin V and cathepsin L inhibitor Biol Chem. 2010 May;391(5):561-70. </a>_x000D_ _x000D_ <strong>Products Related to Cathepsin Inhibitor Peptide can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>