Thiocarlide

Thiocarlide is a potent antibacterial agent. Thiocarlide inhibits Mycobacterium tuberculosis H37Rv, Mycobacterium bovisBCG, Mycobacterium avium, and Mycobacterium aurum A+ with MICs of 2.5, 0.5, 2.0 and 2.0 μg/mL, respectively[1].

Product Specifications

CAS Number

[910-86-1]

Product Name Alternative

Isoxyl

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/thiocarlide.html

Purity

99.0

Solubility

DMSO : 30 mg/mL (ultrasonic;warming)

Smiles

S=C(NC1=CC=C(OCCC(C)C)C=C1)NC2=CC=C(OCCC(C)C)C=C2

Molecular Formula

C23H32N2O2S

Molecular Weight

400.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Phetsuksiri B, et al. Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis. Antimicrob Agents Chemother. 1999 May;43 (5) :1042-51.