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Tunicamine

Product Specifications

CAS Number

66054-53-3

UNSPSC Description

Tunicamine is a high carbohydrate antibiotic that is part of the structure of Tunicamycin. Tunicamycin is a nucleoside antibiotic and a reversible polyprenol-phosphate inhibitor[1][2][3].

Target Antigen

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tunicamine.html

Smiles

O[C@@H]1[C@@H](N)C(O)O[C@H](C[C@@H](O)[C@@H]2[C@@H](O)[C@@H](O)C(O)O2)[C@@H]1O

Molecular Weight

311.29

References & Citations

[1]Astani EK,et al. Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYCB-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations. ACS Omega. 2022 Sep 6;7(37):32970-32987.|[2]Sasai H, et al. Synthetic Approach Toward Antibiotic Tunicamycins-VII Synthesis of Tunicamine and Tunicaminyl Uracil Derivative. Journal of Carbohydrate Chemistry, 1985, 4(1): 99-112.|[3]Tsvetanova BC, et al. Biosynthesis of tunicamycin and metabolic origin of the 11-carbon dialdose sugar, tunicamine. J Biol Chem. 2002 Sep 20;277(38):35289-96.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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