NLRP3-IN-2 (Standard)
NLRP3-IN-2 (Standard) is the analytical standard of NLRP3-IN-2. This product is intended for research and analytical applications. NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism[1].
Product Specifications
CAS Number
16673-34-0
UNSPSC
12352005
Target
NOD-like Receptor (NLR) ; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-2-standard.html
Smiles
O=C(NCCC1=CC=C(S(=O)(N)=O)C=C1)C2=CC(Cl)=CC=C2OC
Molecular Formula
C16H17ClN2O4S
Molecular Weight
368.84
References & Citations
[1]Carlo Marchetti, et al. A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse. J Cardiovasc Pharmacol. 2014 Apr;63 (4) :316-322.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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