Human CD3E & CD3D Heterodimer-coupled Magnetic Beads

Human CD3E & CD3D Heterodimer-coupled Magnetic Beads is expressed from Human -.

Product Specifications

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Origin Species

Human

Target

CD3E & CD3D

Applications

This product is intended for immunocapture, biopanning. This is a non-sterile product.

Stability

Upon receipt, please store the lyophilized beads at -20°C for long term storage. The shelf life is 1 year at -20°C in lyophilized form. Please avoid more than 3 freeze-thaw cycles once reconstitution, immediate use after reconstitution is highly recommended.

Format

Powder

Components

Antibody Purification: 1. Resuspend the lyophilized beads by adding the buffer of choice. 2. Add analyte to the suspension, mix and incubate to enable specific binding of the beads and the target protein. 3. Magnetize beads, remove supernatant, and wash unbound protein fractions to capture target protein-bound beads. 4. Wash, magnetize the beads and collect purified target protein for use in downstream applications.