Human Transforming Growth Factor β2

<strong>Human Transforming Growth Factor Œ≤2</strong>_x000D_ <strong>Catalog number:</strong> B2010334_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Transforming Growth Factor Œ≤2 expressed in HEK 293. This protein acts as a multifunctional cytokine involved in the control of cell growth and differentiation, induces fibrosis and causes the suppression of immune response._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-Œ≤2_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Fischer TW, Herczeg-Lisztes E, Funk W, Zillikens D, B√≠r√≥ T, Paus R._x000D_ Differential effects of caffeine on hair shaft elongation, matrix and outer root_x000D_ sheath keratinocyte proliferation, and transforming growth factor-Œ≤2/insulin-_x000D_ like growth factor-1-mediated regulation of the hair cycle in male and female_x000D_ human hair follicles in vitro. Br J Dermatol. 2014 Nov;171(5):1031-43._x000D_ _x000D_ 2: Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML,_x000D_ Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS,_x000D_ Panettieri RA Jr. Transforming Growth Factor-Œ≤1 Decreases Œ≤₂-Agonist-_x000D_ induced Relaxation in Human Airway Smooth Muscle. Am J Respir Cell Mol Biol._x000D_ 2019 Aug;61(2):209-218._x000D_ _x000D_ 3: Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Pasquale Nigro, Ryan RE,_x000D_ Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM,_x000D_ Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S,_x000D_ Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ. TGF-Œ≤2 is an exercise-induced_x000D_ adipokine that regulates glucose and fatty acid metabolism. Nat Metab. 2019_x000D_ Feb;1(2):291-303._x000D_ _x000D_ 4: Soma T, Tsuji Y, Hibino T. Involvement of transforming growth factor-beta2 in_x000D_ catagen induction during the human hair cycle. J Invest Dermatol. 2002_x000D_ Jun;118(6):993-7._x000D_ _x000D_ 5: Stockis J, Dedobbeleer O, Lucas S. Role of GARP in the activation of latent_x000D_ TGF-Œ≤1. Mol Biosyst. 2017 Sep 26;13(10):1925-1935._x000D_ _x000D_ 6: Ganesan R, Sivalingam N. Transforming Growth Factor Beta 2 Inhibits Growth_x000D_ and Proliferation Potential of Smad4 and p53 Mutated Human Colon Adenocarcinoma_x000D_ Cells. Pathol Oncol Res. 2019 Apr;25(2):819-821. d_x000D_ _x000D_ 7: Su Y, Feng W, Shi J, Chen L, Huang J, Lin T. circRIP2 accelerates bladder_x000D_ cancer progression via miR-1305/Tgf-Œ≤2/smad3 pathway. Mol Cancer. 2020 Feb_x000D_ 4;19(1):23._x000D_ _x000D_ 8: Del Amo-Maestro L, Marino-Puertas L, Goulas T, Gomis-R√ºth FX. Recombinant_x000D_ production, purification, crystallization, and structure analysis of human_x000D_ transforming growth factor Œ≤2 in a new conformation. Sci Rep. 2019 Jun_x000D_ 17;9(1):8660. 9: Matta B, Bora PS, Neuhouser AJ, Bora NS. Inhibitory role of transforming_x000D_ growth factor Œ≤2 in experimental autoimmune anterior uveitis. Graefes Arch Clin_x000D_ Exp Ophthalmol. 2019 May;257(5):953-960._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21668782/">10: Ma J, Zhang Q, Moe MC, Zhu T. Regulation of cell-mediated collagen gel_x000D_ contraction in human retinal pigment epithelium cells by vascular endothelial_x000D_ growth factor compared with transforming growth factor-Œ≤2. Clin Exp Ophthalmol._x000D_ 2012 Jan-Feb;40(1):e76-86. </a>_x000D_ _x000D_ <strong>Products Related to Human Transforming Growth Factor Œ≤2 </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>