S1R agonist 1
Product Specifications
UNSPSC Description
S1R agonist 1 (Compound 6b) is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 exhibits neuroprotection against ROS and NMDA-induced neurotoxicity[1].
Target Antigen
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s1r-agonist-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(OCCN2CCC(CC2)CC3=CC=CC=C3)=CC=CC=C1
Molecular Weight
295.42
References & Citations
[1]Linciano P, et al. Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents. Eur J Med Chem. 2023 Mar 5;249:115163.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149803/S1R-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149803/S1R-agonist-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
193354-70-0
Available Sizes
Curated Selection
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