Nek2/Hec1-IN-1
N-[4- (2,4-Dimethylphenyl) -2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively) .
Product Specifications
CAS Number
560103-80-2
Product Name Alternative
Nec2/Hec1 inhibitor
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nek2-hec1-in-1.html
Smiles
O=C(C1=CC=NC=C1)NC2=NC(C3=CC=C(C)C=C3C)=CS2
Molecular Formula
C17H15N3OS
Molecular Weight
309.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Qiu, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J. Med. Chem. 52 (6), 1757-1767 (2009) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![YB1 (YBX1) Mouse Monoclonal Antibody [Clone ID: OTI7B4]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907e6a/imageurl/cf806164.webp)
YB1 (YBX1) Mouse Monoclonal Antibody [Clone ID: OTI7B4]
