Bepridil (hydrochloride)

Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.

Product Specifications

CAS Number

[68099-86-5]

Product Name Alternative

CERM 1978

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Bepridil_hydrochloride.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 12.5 mg/mL (ultrasonic)

Smiles

CC(C)COCC(N1CCCC1)CN(C2=CC=CC=C2)CC3=CC=CC=C3.[H]Cl

Molecular Formula

C24H35ClN2O

Molecular Weight

403.00

Precautions

H302, H315, H319, H335

References & Citations

[1]Flaim SF, et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics, coronary vascular resistance, and cardiac output distribution in normal, conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11 (3) :363-72.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Acta Pharmacol Sin. 2025 May;46 (5) :1190-1204.|Biochem Biophys Res Commun. 2025 Oct 30:786:152756.|bioRxiv. 2025 Nov 21:2025.11.20.689520.|Eur J Pharm Sci. 2021 Sep 1:164:105889.|Eur J Pharm Sci. 2023 Aug 1:187:106475.|Research Square Preprint. 2024 Feb 9.|Virology. 2020 Jan 2;539:38-48.|Università Vita-Salute San Raffaele. 2022 Apr 08. 34.