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Bfl-1-IN-4

Bfl-1-IN-4 (Compound 8) is an inhibitor for Bcl-2 associated protein A1 (Bfl-1) with an IC50 of 16.8 μM[1].

Product Specifications

CAS Number

[3075570-86-1]

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bfl-1-in-4.html

Smiles

C=CC(N(CC1=CC=CC=C1OCC(N)=O)C2=CC=C(Cl)C=C2)=O

Molecular Formula

C18H17ClN2O3

Molecular Weight

344.79

References & Citations

[1]Lucas SCC, et al., Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1. J Med Chem. 2024 Jun 25.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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