Human 3-Hydroxyacyl-CoA Dehydrogenase Type-2 (HSD17B10)

<strong>Human 3-Hydroxyacyl-CoA Dehydrogenase Type-2 (HSD17B10)</strong>_x000D_ <strong>Catalog number:</strong> B2015513_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 28 kDa (271 aa)_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> hydroxysteroid 17-beta dehydrogenase 10, 17 beta hydroxysteroid dehydrogenase 10, 17 beta hydroxysteroid dehydrogenase type 10, 17-beta-hydroxysteroid dehydrogenase 10, 17-beta-HSD 10, 17b-HSD10, 17b HSD10, 3 hydroxy 2 methylbutyryl CoA dehydrogenase, 3 hydroxyacyl CoA dehydrogenase type 2, 3 hydroxyacyl CoA dehydrogenase type II, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3-hydroxyacyl-CoA dehydrogenase type-2, AB binding alcohol dehydrogenase, ABAD, Ads9, Amyloid beta binding polypeptide, Amyloid beta peptide binding alcohol dehydrogenase, Amyloid beta peptide binding protein, CAMR, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, DUPXp11.22, Endoplasmic Reticulum Amyloid Binding Protein, Endoplasmic reticulum associated amyloid beta peptide binding protein, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, ER associated amyloid beta-binding protein, ERAB_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: van Hove EC, Hansen T, Dekker JM, Reiling E, Nijpels G, Jørgensen T, Borch-Johnsen K, Hamid YH, Heine RJ, Pedersen O, Maassen JA, 't Hart LM. The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study Diabetes. 2006 Nov;55(11):3193-6._x000D_ 2: Lai X, Umbricht CB, Fisher K, Bishop J, Shi Q, Chen S. Identification of novel biomarker and therapeutic target candidates for diagnosis and treatment of follicular carcinoma J Proteomics. 2017 Aug 23;166:59-67._x000D_ 3: Zhou Y, Wynia-Smith SL, Couvertier SM, Kalous KS, Marletta MA, Smith BC, Weerapana E. Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2 Cell Chem Biol. 2016 Jun 23;23(6):727-37._x000D_ 4: Louden ED, Luzzo KM, Jimenez PT, Chi T, Chi M, Moley KH. TallyHO obese female mice experience poor reproductive outcomes and abnormal blastocyst metabolism that is reversed by metformin Reprod Fertil Dev. 2014 Dec;27(1):31-9._x000D_ 5: Lammers G, Poelkens F, van Duijnhoven NT, Pardoel EM, Hoenderop JG, Thijssen DH, Hopman MT. Expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle Am J Physiol Endocrinol Metab. 2012 Nov 15;303(10):E1245-51._x000D_ 6: Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J. Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol PLoS One. 2011;6(12):e28887._x000D_ 7: Takahashi K, Kitaoka Y, Matsunaga Y, Hatta H. Effects of lactate administration on mitochondrial enzyme activity and monocarboxylate transporters in mouse skeletal muscle Physiol Rep. 2019 Sep;7(17):e14224._x000D_ 8: Qin YM, Poutanen MH, Novikov DK. Substrate specificities of peroxisomal members of short-chain alcohol dehydrogenase superfamily: expression and characterization of dehydrogenase part of Candida tropicalis multifunctional enzyme J Lipid Res. 2000 Jan;41(1):93-8._x000D_ 9: Lantz KA, Vatamaniuk MZ, Brestelli JE, Friedman JR, Matschinsky FM, Kaestner KH. Foxa2 regulates multiple pathways of insulin secretion J Clin Invest. 2004 Aug;114(4):512-20._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37333553">10: Christensen DL, Mutabingwa TK, Bygbjerg IC, Vaag AA, Grunnet LG, Lajeunesse-Trempe F, Nielsen J, Schmiegelow C, Ramaiya KL, Myburgh KH. Skeletal muscle fibre type and enzymatic activity in adult offspring following placental and peripheral malaria exposure in foetal life Front Public Health. 2023 Jun 2;11:1122393. </a>_x000D_ _x000D_ <strong>Products Related to Human 3-Hydroxyacyl-CoA Dehydrogenase Type-2 (HSD17B10) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>