Rociverine
Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity[1].
Product Specifications
CAS Number
[53716-44-2]
UNSPSC
12352211
Hazard Statement
H302
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rociverine.html
Smiles
O[C@@]1(C2CCCCC2)[C@H](CCCC1)C(OC(C)CN(CC)CC)=O
Molecular Formula
C20H37NO3
Molecular Weight
339.51
Precautions
P264-P270-P330-P501
References & Citations
[1]Stereoselective inhibition of muscarinic receptor subtypes by the eight stereoisomers related to rociverine
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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