Lanepitant (dihydrochloride)
Lanepitant dihydrochloride (LY303870 dihydrochloride) is a non-peptide neurokinin-1 receptor antagonist. Lanepitant dihydrochloride has analgesic and anti-inflammatory activities[1][2].
Product Specifications
CAS Number
170508-05-1
Product Name Alternative
LY303870 (dihydrochloride)
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lanepitant-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
COC(C=CC=C1)=C1CN(C(C)=O)C[C@H](NC(CN2CCC(N3CCCCC3)CC2)=O)CC4=CNC5=C4C=CC=C5.Cl.Cl
Molecular Formula
C33H47Cl2N5O3
Molecular Weight
632.66
References & Citations
[1]Goldstein DJ, et al. Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia. 2001 Mar;21 (2) :102-6.|[2]Goldstein DJ, et al. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain. Clin Pharmacol Ther. 2000 Apr;67 (4) :419-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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