Serpin I2, Human (HEK293, His)

Serpin I2 Protein, is a member of the serpin (serine protease inhibitor) superfamily. Serpin I2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin. Serpin I2 is downregulated in pancreatic and breast cancer, and associated with acinar cell apoptosis and pancreatic insufficiency when absent in mice. Serpin I2 is associated with refractive error and has the potential for further investigations of the genetic susceptibility to myopia research[1][2]. Serpin I2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin I2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin I2 Protein, Human (HEK293, His) is 387 a.a., with molecular weight of 44-60 kDa.

SRCSAQKNTE FAVDLYQEVS LSHKDNIIFS PLGITLVLEM VQLGAKGKAQ QQIRQTLKQQ ETSAGEEFFV LKSFFSAISE KKQEFTFNLA NALYLQEGFT VKEQYLHGNK EFFQSAIKLV DFQDAKACAE MISTWVERKT DGKIKDMFSG EEFGPLTRLV LVNAIYFKGD WKQKFRKEDT QLINFTKKNG STVKIPMMKA LLRTKYGYFS ESSLNYQVLE LSYKGDEFSL IIILPAEGMD IEEVEKLITA QQILKWLSEM QEEEVEISLP RFKVEQKVDF KDVLYSLNIT EIFSGGCDLS GITDSSEVYV SQVTQKVFFE INEDGSEAAT STGIHIPVIM SLAQSQFIAN HPFLFIMKHN PTESILFMGR VTNPDTQEIK GRDLDSL