Dusquetide (TFA)
Dusquetide (SGX942) TFA is a first-in-class innate defense regulator (IDR) . Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection[1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns
Product Specifications
Product Name Alternative
SGX942 (TFA)
UNSPSC
12352209
Target
Bacterial; p62
Type
Peptides
Related Pathways
Anti-infection; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/dusquetide-tfa.html
Purity
98.49
Solubility
10 mM in DMSO
Smiles
C[C@@H](C(N)=O)NC([C@H]1N(C([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC1)=O.OC(C(F)(F)F)=O
Molecular Formula
C27H48F3N9O7
Molecular Weight
667.72
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
Phase 3
Available Sizes
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