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Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit) . The high and intermediate affinity forms also associate with a gamma subunit.

Product Specifications

Background

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit) . The high and intermediate affinity forms also associate with a gamma subunit.

Host

HEK293

Origin Species

Human

Target

IL-2 R beta & IL-2 R gamma

Tag

Luc

Applications

• Bioactivity detection of human IL-2 fusion protein • Bioactivity detection of human IL-15 fusion protein

Format

Liquid

Shipping Conditions

Dry ice

Storage Conditions

Frozen in liquid nitrogen

Package Size

1Vial*2

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/CHEK-ATF136.pdf

Species

Human

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