5-trans U-46619

5-trans U-46619 is a PGE synthase inhibitor. At a concentration of 10 μM, 5-trans U-46619 inhibits PGE synthase by [1].

Product Specifications

CAS Number

[330796-58-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PGE synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-trans-u-46619.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C/C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])CO2)/C=C/[C@@H](O)CCCCC)=O

Molecular Formula

C21H34O4

Molecular Weight

350.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Quraishi O, Mancini J A, Riendeau D. Inhibition of inducible prostaglandin E2 synthase by 15-deoxy-Δ12, 14-prostaglandin J2 and polyunsaturated fatty acids[J]. Biochemical pharmacology, 2002, 63 (6) : 1183-1189.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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