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RA-0002034

RA-0002034 is a Chikungunya virus (CHIKV) nsP2 protease inhibitor with an IC50 of 58 nM. RA-0002034 covalently modifies the catalytic cysteine in a site-specific manner[1].

Product Specifications

CAS Number

[3038542-51-4]

Product Name Alternative

RA-2034

UNSPSC

12352005

Target

CHIKV; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ra-0002034.html

Purity

99.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC1=C(C2=CC(C(NC/C=C/S(C)(=O)=O)=O)=NN2)C=CC=C1

Molecular Formula

C16H19N3O4S

Molecular Weight

349.40

References & Citations

[1]Eric M Merten, et al. Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach. bioRxiv[Preprint]. 2024 May 23:2024.03.22.586341.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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