SCH 39304
SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research[1].
Product Specifications
CAS Number
120924-80-3
Product Name Alternative
SM-8668
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sch-39304.html
Smiles
CS([C@@H](C)[C@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
Molecular Formula
C13H15F2N3O3S
Molecular Weight
331.34
References & Citations
[1]Tanio T, et al. In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent. Antimicrob Agents Chemother. 1990 Jun;34 (6) :980-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Frequently Asked Questions
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