Human TATA Box Binding Protein (TBP), 39 kDa

<strong>Human TATA Box Binding Protein (TBP), 39 kDa</strong>_x000D_ <strong>Catalog number:</strong> B2014396_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 39 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> GTF2D, GTF2D1, HDL4, MGC117320, TFIID_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Hardivill S, Banerjee PS, Selen Alpergin ES, Smith DM, Han G, Ma J, Talbot CC Jr, Hu P, Wolfgang MJ, Hart GW. TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation Mol Cell. 2020 Mar 5;77(5):1143-1152.e7._x000D_ 2: Tjitro R, Campbell LA, Basova L, Johnson J, Najera JA, Lindsey A, Marcondes MCG. Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure Front Immunol. 2019 Feb 4;9:3110._x000D_ 3: Magri S, Nanetti L, Gellera C, Sarto E, Rizzo E, Mongelli A, Ricci B, Fancellu R, Sambati L, Cortelli P, Brusco A, Bruzzone MG, Mariotti C, Di Bella D, Taroni F. Digenic inheritance of STUB1 variants and TBP polyglutamine expansions explains the incomplete penetrance of SCA17 and SCA48 Genet Med. 2022 Jan;24(1):29-40._x000D_ 4: Arkova O, Kuznetsov N, Fedorova O, Savinkova L. A real-time study of the interaction of TBP with a TATA box-containing duplex identical to an ancestral or minor allele of human gene LEP or TPI J Biomol Struct Dyn. 2017 Nov;35(14):3070-3081._x000D_ 5: Zabierowski SE, Deluca NA. Stabilized binding of TBP to the TATA box of herpes simplex virus type 1 early (tk) and late (gC) promoters by TFIIA and ICP4 J Virol. 2008 Apr;82(7):3546-54._x000D_ 6: Berciano J. Commentary Mov Disord. 2014 Jan;29(1):38-9._x000D_ 7: Delgadillo RF, Whittington JE, Parkhurst LK, Parkhurst LJ. The TATA-binding protein core domain in solution variably bends TATA sequences via a three-step binding mechanism Biochemistry. 2009 Mar 3;48(8):1801-9._x000D_ 8: Nakamori M, Panigrahi GB, Lanni S, Gall-Duncan T, Hayakawa H, Tanaka H, Luo J, Otabe T, Li J, Sakata A, Caron MC, Joshi N, Prasolava T, Chiang K, Masson JY, Wold MS, Wang X, Lee MYWT, Huddleston J, Munson KM, Davidson S, Layeghifard M, Edward LM, Gallon R, Santibanez-Koref M, Murata A, Takahashi MP, Eichler EE, Shlien A, Nakatani K, Mochizuki H, Pearson CE. A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo Nat Genet. 2020 Feb;52(2):146-159._x000D_ 9: Blair RH, Goodrich JA, Kugel JF. Using FRET to monitor protein-induced DNA bending: the TBP-TATA complex as a model system Methods Mol Biol. 2013;977:203-15._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21705419">10: Huang S, Ling JJ, Yang S, Li XJ, Li S. Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor Brain. 2011 Jul;134(Pt 7):1943-58. </a>_x000D_ _x000D_ <strong>Products Related to Human TATA Box Binding Protein (TBP), 39 kDa can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>